California Pharmacy Jurisprudence Exam (CPJE) Practice 2026 - Free CPJE Practice Questions and Study Guide

A pharmacist can change the strength of a medication after it has been prescribed only with prescriber authorization. This is important because medication adjustments, including changes in strength, can significantly impact the treatment outcome for the patient. Pharmacists are trained professionals who understand the pharmacokinetics and pharmacodynamics of drugs, but they must operate within the scope of collaborative practice agreements or prescription authority. By obtaining authorization from the prescriber, the pharmacist ensures that the change is appropriate and safe for the patient, maintaining clear communication within the healthcare team.

Other options suggest that pharmacists can make changes autonomously, based on patient requests, or for any medication upon filling, which does not align with the legal and ethical responsibilities that pharmacies and pharmacists hold within the healthcare system. Balancing clinical judgment with adherence to regulatory standards is key to safe pharmacy practice.